Prevalence of Dyslipidemia and Its Association with Lifestyle Choices Among Pakistani Adults: A Cross-Sectional Study

Assessing Lifestyle Impacts on Lipid Profiles in Pakistani Adults

Authors

  • Taimour Mushtaq Lahore Medical & Dental College (LM&DC), Lahore, Pakistan Author
  • Abdullah Farooq Lahore Medical & Dental College (LM&DC), Lahore, Pakistan Author
  • Isha Ambreen Lahore Medical & Dental College (LM&DC), Lahore, Pakistan Author
  • Maeda Usmani Ghurki Trust Teaching Hospital, Lahore, Pakistan Author
  • Osama Irshad Ghurki Trust Teaching Hospital, Lahore, Pakistan Author
  • Muhammad Salman Avicenna Medical College, Lahore, Pakistan Author

DOI:

https://doi.org/10.69750/dmls.02.01.098

Keywords:

Dyslipidemia, Cardiovascular Diseases, Urbanization, Lifestyle Factors, Physical Inactivity, Obesity, Pakistan, Lipid Profile

Abstract

Background: Dyslipidemia is a major risk factor for CVD, the leading cause of global morbidity and mortality. Dyslipidemia is rising rapidly in low- and middle-income countries like Pakistan because of urbanization, sedentary lifestyles, and changes in diet. Determinants of dyslipidemia are essential to understand the prevalence and development of effective public health strategies, but information on its association with lifestyle factors is limited in the Pakistani population.

Objectives: The study objectives were to determine the prevalence of dyslipidemia and examine its association with modifiable lifestyle factors such as physical inactivity, dietary patterns, cigarette smoking, and obesity in Pakistani adults.

Methods: A cross-sectional study was conducted in Ghurki Trust and Teaching Hospital, Pakistan, from December 2023 to December 2024. Structured interviews and clinical assessments, as well as fasting lipid profile measurements, were completed by participants. Dyslipidemia was defined as total cholesterol ≥200 mg/dL, LDL cholesterol ≥130 mg/dL, HDL cholesterol <40 mg/dL for men or <50 mg/dL for women, and triglycerides >150 mg/dL. Associations between lifestyle factors and dyslipidemia were assessed by logistic regression analysis controlling for age and sex.

Results: The overall prevalence of dyslipidemia was 79.3% (95% CI: 72.8–84.7) in the population. It was found that 65.7% of participants had low HDL-C, 50.3% had hypertriglyceridemia, 43.1% had hypercholesterolemia, and 39.7% had elevated LDL-C. Predictors included urban residence, physical inactivity, high saturated fat intake, and obesity.

Conclusion: The high prevalence of dyslipidemia among Pakistani adults suggests that public health interventions aimed at lifestyle modification, early screening, and reducing CVD burden are necessary.

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References

Sarfraz M, Sajid S, Ashraf MA. Prevalence and pattern of dyslipidemia in hyperglycemic patients and its associated factors among Pakistani population. Saudi Journal of Biological Sciences. 2016;23(6):761-6.doi: 10.1016/j.sjbs.2016.03.001

Muhammed AA, Afzaal M, Khan MJ, Baig AM, Aasim M. Frequency and pattern of dyslipidemia and its association with other risk factors among Type-2 Diabetics. Pakistan Journal of Medical Sciences. 2025;41(2):472-7.doi: 10.12669/pjms.41.2.10264

Sharif H, Sheikh SS, Seemi T, Naeem H, Khan U, Jan SS. Metabolic syndrome and obesity among marginalised school-going adolescents in Karachi, Pakistan: a cross-sectional study. The Lancet Regional Health - Southeast Asia. 2024;21.doi: 10.1016/j.lansea.2024.100354

Ali N, Samadder M, Kathak RR, Islam F. Prevalence and factors associated with dyslipidemia in Bangladeshi adults. PLOS ONE. 2023;18(1):e0280672.doi: 10.1371/journal.pone.0280672

Hussain A, Zakria M, Ali I, Tariq SA, Hussain A, Siraj S. Pattern of dyslipidemia and associated factors in coronary artery disease patients in Khyber Pakhtunkhwa: A cross-sectional secondary data analysis. Pak J Med Sci. 2023;39(5):1416-21.doi: 10.12669/pjms.39.5.7382

Ali I, Kharma A, Samara M, Odeh S, Jaradat N, Zaid AN, et al. Prevalence of Dyslipidemia in Undiagnosed Palestinian Men: A Cross-Sectional Study. Journal of Lipids. 2019;2019(1):3473042.doi: 10.1155/2019/3473042

Safdar NF, Bertone-Johnson E, Cordeiro L, Jafar TH, Cohen NL. Do dietary patterns explain high prevalence of cardiovascular risk factors among Pakistani urban adults? A cross-sectional study. BMC Nutrition. 2016;2(1):58.doi: 10.1186/s40795-016-0097-z

Ali N, Kathak RR, Fariha KA, Taher A, Islam F. Prevalence of dyslipidemia and its associated factors among university academic staff and students in Bangladesh. BMC Cardiovascular Disorders. 2023;23(1):366.doi: 10.1186/s12872-023-03399-1

Siddique AH, Ahmad I, Hafeez M, Khadim R, Aziz S, Iqbal T, et al. HYPERLIPIDEMIA PATTERNS IN NEWLY DIAGNOSED YOUNG DIABETIC SOLDIERS: A DESCRIPTIVE CROSS-SECTIONAL STUDY. Pakistan Armed Forces Medical Journal. 2018;68(Suppl-1):S5-9.

Sadiq F, Shafi S, Sikonja J, Khan M, Ain Q, Khan MI, et al. Mapping of familial hypercholesterolemia and dyslipidemias basic management infrastructure in Pakistan: a cross-sectional study. The Lancet Regional Health - Southeast Asia. 2023;12.doi: 10.1016/j.lansea.2023.100163

Das H, Banik S. Prevalence of dyslipidemia among the diabetic patients in southern Bangladesh: A cross-sectional study. Diabetes & Metabolic Syndrome: Clinical Research & Reviews. 2019;13(1):252-7.doi: 10.1016/j.dsx.2018.09.006

Wang W, Li X, Lv D, Wu X, Xie F, Xie W, et al. Analyzing lipid profiles and dyslipidemia prevalence in hypertensive patients: a cross-sectional study from primary community health institutions. Frontiers in Medicine. 2024;11.doi: 10.3389/fmed.2024.1425414

Lone SS, Majid S, Bhat MH, Wani GA. Exploring the burden of mixed dyslipidemia in patients with type 2 diabetes mellitus: A cross-sectional study in Kashmir, India. American Journal of Human Biology. 2024;36(4):e24012.doi: 10.1002/ajhb.24012

Abera A, Worede A, Hirigo AT, Alemayehu R, Ambachew S. Dyslipidemia and associated factors among adult cardiac patients: a hospital-based comparative cross-sectional study. European Journal of Medical Research. 2024;29(1):237.doi: 10.1186/s40001-024-01802-x

Hanif MK, Fan Y, Wang L, Jiang H, Li Z, Ma M, et al. Dietary Habits of Patients with Coronary Artery Disease: A Case-Control Study from Pakistan. International Journal of Environmental Research and Public Health [Internet]. 2022; 19(14).doi: 10.3390/ijerph19148635

Pengpid S, Peltzer K. National high prevalence, and low awareness, treatment and control of dyslipidaemia among people aged 15–69 years in Mongolia in 2019. Scientific Reports. 2022;12(1):10478.doi: 10.1038/s41598-022-14729-2

Abdissa D, Hirpa D. Dyslipidemia and its associated factors among adult diabetes outpatients in West Shewa zone public hospitals, Ethiopia. BMC Cardiovascular Disorders. 2022;22(1):39.doi: 10.1186/s12872-022-02489-w

Haider N, Abbas U, Arif HE, Uqaili AA, Khowaja MA, Hussain N, et al. From plate to profile: investigating the influence of dietary habits and inactive lifestyle on lipid profile in medical students at clerkship. BMC Nutrition. 2024;10(1):71.doi: 10.1186/s40795-024-00871-9

Asif M, Aslam M, Altaf S, Atif S, Majid A. Prevalence and Sociodemographic Factors of Overweight and Obesity among Pakistani Adults. J Obes Metab Syndr. 2020;29(1):58-66.doi: 10.7570/jomes19039

Bhanji S, Khuwaja AK, Siddiqui F, Azam I, Kazmi K. Underestimation of weight and its associated factors among overweight and obese adults in Pakistan: a cross sectional study. BMC Public Health. 2011;11(1):363.doi: 10.1186/1471-2458-11-363

Pengpid S, Peltzer K. Prevalence, awareness, treatment, and control of dyslipidemia and associated factors among adults in Jordan: Results of a national cross-sectional survey in 2019. Preventive Medicine Reports. 2022;28:101874.doi: 10.1016/j.pmedr.2022.101874

Khan MSN, Khan MI, Saqlain A, Umer S, Haider M, Ashiq K. Evaluation of Cardiovascular Risk Factors and Their Association With Coronary Artery Disease in Pakistani Adults. Cureus. 2024;16(7):e64670.doi: 10.7759/cureus.64670

Zaid M, Hasnain S. Plasma lipid abnormalities in Pakistani population: trends, associated factors, and clinical implications. Brazilian Journal of Medical and Biological Research. 2018;51.

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Published

08-03-2025

How to Cite

Mushtaq, T. ., Farooq, A. ., Ambreen, I. ., Usmani, M. ., Irshad, O. ., & Salman, M. . (2025). Prevalence of Dyslipidemia and Its Association with Lifestyle Choices Among Pakistani Adults: A Cross-Sectional Study: Assessing Lifestyle Impacts on Lipid Profiles in Pakistani Adults. DEVELOPMENTAL MEDICO-LIFE-SCIENCES, 2(1), 34-41. https://doi.org/10.69750/dmls.02.01.098

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