Postoperative Outcomes of Breast Cancer Surgery in Tertiary Care Units in Pakistan: A Cross-Sectional Study
Infection Rates and Wound Healing in Post-Mastectomy Patients
DOI:
https://doi.org/10.69750/dmls.01.04.038Keywords:
Breast Cancer, Postoperative, Patient Recovery, Surgical ComplicationsAbstract
Background: Breast cancer is a serious health problem in Pakistan and has high incidence and mortality rate. This paper seeks to compare and contrast surgical care and patient management by analyzing postoperative results of breast cancer operations in tertiary health care centers of Pakistan.
Methods: It was a cross-sectional study designed in tertiary care unit of Nishtar hospital Multan where medical records of female breast cancer patients who underwent surgery between January 2024 to June 2024 were analyzed. The demographic data, surgical procedures, postoperative morbidities, hospital stays, and readmission rates data were analyzed using multivariate statistics.
Results: In total 300 patients were selected in the study. The rate of developing post-operative complications was 20%, and the most frequent of them were infections (12%). The mean days to recovery including those who were discharged and stayed at home was twenty-one days with a readmission ratio of fifteen percent. Specific factors that were found to have a significant influence on the outcomes consisted of age, comorbidities as well as the surgical method used with the latter having a (p ≤ 0.01).
Conclusion: This finding of study stated that the postoperative outcomes of breast cancer surgeries in Pakistani tertiary care units were determined by patients’ characteristics, medical co morbidities, and surgical procedures. Implementing standard of care and making available better surgical modalities can improve the patient care and post-surgical care maybe reduced the rate of further complications among breast cancer patients.
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Mooghal M, Javaid RH, Khan W, Muneeb M, Khan WA, Ahmad A, et al. COVID 19 pandemic: Effect on management of patients with breast cancer; single center retrospective cohort study. International Journal of Surgery Open. 2021;35:100386.doi:10.1016/j.ijso.2021.100386
Sakina Abidi S, Mushtaque Vohra L, Rizwan Javed M, Khan N. Oncoplastic surgery: A suitable alternative to conventional breast conserving surgery in low - Middle income countries; a retrospective cohort study. Annals of Medicine and Surgery. 2021;68:102618. doi:10.1016/ j.amsu.2021.102618
Vohra LM, Jabeen D, Asif N, Ahad A. COVID-19 pandemic and breast cancer management: A retrospective observational clinical study from Pakistan. Annals of Medicine and Surgery. 2021;63.doi: 10.1016/j.amsu.2021.01.099
Khalid IB, Sarwar A, Khalid HB, Sajjad B, Rehman B, Parvaiz MA. Clinicopathological Features and Treatment Outcomes of Male Breast Cancer in Pakistani Population: A 10-Year Retrospective Cross-Sectional Study. Breast Cancer: Basic and Clinical Research. 2024;18.doi:10.1177/11782 234241233120
Ali G, Shaukat A, Sarfraz U, Masood S, Jamshaid K. Surgical Management of Breast Cancer during COVID-19 Pandemic. Annals of King Edward Medical University. 2024;30(2):145-51.doi: 10.21649/akemu.v30i2.5560
Vohra LM, Soomro R, Jabeen D, Ali N, Khan N. Utility of post mastectomy radiotherapy among patients with T1/ T2 N1 disease: A retrospective cohort study. Annals of Medicine and Surgery. 2021;65:102295.doi:10.1016/j.amsu.2021.102295
Vohra LM, Jabeen D, Khan N, Nizar A, Jamil A, Siddiqui T. Analysing the trends in breast surgery practice during COVID-19 pandemic: A comparative study with the Pre-COVID era. Annals of Medicine and Surgery. 2022;74:103342.doi: 10.1016/j.amsu.2022.103 342
Jamshed A, Shah M, Syed A, Murtaza G, Mehmood T, Chaudry S, et al. Clinical outcome of primary non-metastatic breast cancer: A single institution experience. Indian Journal of Cancer. 2015;52(1):119-25.doi: 10.4103/0019-509x.175599
Rashid M, Shahbaz MN, Akram A, Anwar A, Umar M, Ali MS, et al. Analysis of Patients Receiving Treatment for Inflammatory Breast Disease at Surgery Department of Tertiary Care Units: Treating Inflammatory Breast Disease in Tertiary Surgery Units. DEVELOPMENTAL MEDICO-LIFE-SCIENCES. 2024;1(1):2-6.doi:10.6 9750/dmls.01.01.012
Nair N, Shet T, Parmar V, Havaldar R, Gupta S, Budrukkar A, et al. Breast cancer in a tertiary cancer center in India - An audit, with outcome analysis. Indian Journal of Cancer. 2018;55(1):16-22.doi: 10.4103/ijc.IJC_484_17
Collaborative O-GAA. Textbook outcome following oesophagectomy for cancer: international cohort study. British Journal of Surgery. 2022;109(5):439-49.doi: 10.1093/bjs/ znac016
Ali B, Mubarik F, Zahid N, Sattar AK. Clinicopathologic Features Predictive of Distant Metastasis in Patients Diagnosed With Invasive Breast Cancer. JCO Global Oncology. 2020(6):1346-51.doi: 10.1200/go.20.00257
Ali D, Zeeshan S, Farooqi N, Vohra L. Breast surgery super-specialization: Impact on advanced surgical training and research. Pak J Med Sci. 2022;38(8):2345-9.doi:10.12669/pjms. 38.8.6045
Bajpai J, Ventrapati P, Joshi S, Wadasadawala T, Rath S, Pathak R, et al. Unique challenges and outcomes of young women with breast cancers from a tertiary care cancer centre in India. The Breast. 2021;60:177-84.doi: 10.1016/j.breast. 2021.09.008
Prodhan AHMSU, Islam DZ, Khandker SS, Jamiruddin MR, Abdullah A, Godman B, et al. Breast Cancer Management in the Era of Covid-19; Key Issues, Contemporary Strategies, and Future Implications. Breast Cancer: Targets and Therapy. 2023;15(null):51-89.doi: 10.2147/ BCTT.S390296
Mansha MA, Sadaf T, Waheed A, Munawar A, Rashid A, Chaudry SJ. Long-Term Toxicity and Efficacy of Intensity-Modulated Radiation Therapy in Cervical Cancers: Experience of a Cancer Hospital in Pakistan. JCO Global Oncology. 2020(6):1639-46.doi: 10.1200/go.20. 00169
Riad A, Knight SR, Ghosh D, Kingsley PA, Lapitan MC, Parreno-Sacdalan MD, et al. Impact of malnutrition on early outcomes after cancer surgery: an international, multicentre, prospective cohort study. The Lancet Global Health. 2023;11(3):e341-e9.doi:10.1016/S2214 -109X(22)00550-2
Shamim Seth U, Perveen S, Ahmed T, Kamal MT, Soomro JA, Murtaza Khomusi M, et al. Postoperative Analgesia in Modified Radical Mastectomy Patients After Instillation of Bupivacaine Through Surgical Drains. Cureus. 2022;14(4):e24125.doi: 10.7759/cureus.24125
Jafar D, Pesnani F, Arif S, Nasir A. Self-Esteem of Patients Receiving Chemotherapy Treatment in a Tertiary Care Hospital Karachi, Pakistan. Pakistan Journal of Medicine and Dentistry. 2020;9(3):60-4.doi: 10.36283/PJMD9-3/012
Cata JP, Zaidi Y, Guerra-Londono JJ, Kharasch ED, Piotrowski M, Kee S, et al. Intraoperative methadone administration for total mastectomy: A single center retrospective study. Journal of Clinical Anesthesia. 2024;98:111572.doi: https://doi.org/10.1016/j.jclinane.2024.111572
Ostermann M, Raimundo M, Williams A, Whiteley C, Beale R. Retrospective analysis of outcome of women with breast or gynaecological cancer in the intensive care unit. JRSM Short Reports. 2013;4(1):1-5.doi: 10.1258/shorts.2012.012036
Alam T, Qureshi R, Aziz M, Khan A. INCIDENCE OF ACCIDENTAL AWARENESS DURING GENERAL ANESTHESIA – A TERTIARY CANCER CARE HOSPITAL EXPERIENCE. Journal of Postgraduate Medical Institute. 2022;36(1):3-8.doi: 10.54079/jpmi.36.1.2996
Rastogi K, Jain S, Bhatnagar AR, Bhaskar S, Gupta S, Sharma N. A comparative study of hypofractionated and conventional radiotherapy in postmastectomy breast cancer patients. Asia-Pacific Journal of Oncology Nursing. 2018;5(1):107-13.doi:10.4103/apjon. apjon_46_ 17
Ahmed O, Asghar MS, Khurshaidi MN, Yasmin F, Kanwal N, Khokher AJ, et al. Provision of Surgical Services to COVID-19-Infected Patients at a Tertiary Care Center in Pakistan: A One-Year Clinical Review of the Year 2020 in General Surgery Department. Cureus. 2021;13(1): e12705.doi: 10.7759/cureus.12705
Shaw JF, Budiansky D, Sharif F, McIsaac DI. The Association of Frailty with Outcomes after Cancer Surgery: A Systematic Review and Metaanalysis. Annals of Surgical Oncology. 2022;29(8):4690-704.doi: 10.1245/s10434-021-11321-2
Pangarsa EA, Rizky D, Tandarto K, Setiawan B, Santosa D, Hadiyanto JN, et al. The effect of multidisciplinary team on survival rates of women with breast cancer: a systematic review and meta-analysis. Annals of Medicine and Surgery. 2023;85(6):2940-8.doi: 10.1097/ms9. 0000000000000914
Satti MZ, Hamza M, Sajid Z, Asif O, Ahmed H, Zaidi SMJ, et al. Compliance Rate of Surgical Antimicrobial Prophylaxis and its Association with Knowledge of Guidelines Among Surgical Residents in a Tertiary Care Public Hospital of a Developing Country. Cureus. 2019;11(5):e4776. doi: 10.7759/cureus.4776
Mustafa F, Khan MA, Mustafa A, Manzoor A, Safa S, Khogyani S. Common Organisms causing surgical site infection(SSI) in Postoperative patients in a tertiary care Hospital. Journal of Rawalpindi Medical College. 2022;26(4).doi: 10.37939/jrmc.v26i4.1982
Yfantis A, Sarafis P, Moisoglou I, Tolia M, Intas G, Tiniakou I, et al. How breast cancer treatments affect the quality of life of women with non-metastatic breast cancer one year after surgical treatment: a cross-sectional study in Greece. BMC Surgery. 2020;20(1):210.doi: 10.1186/s1 2893-020-00871-z
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