Advancements in Predictive Analytics for Early Detection of Myocardial Infarction in High-Risk Populations

Early Detection of Myocardial Infarction Using Predictive Analytics

Authors

  • Farazia Tariq Lahore Medical & Dental College (LM&DC), Lahore, Pakistan Author
  • Ribqa Tariq University Medical and Dental College Faisalabad, Pakistan Author
  • Shan-e-Zahra Saif Lahore Medical & Dental College (LM&DC), Lahore, Pakistan Author
  • Romesa Saqib Lahore Medical & Dental College (LM&DC), Lahore, Pakistan Author
  • Aqsa Saleem Lahore Medical & Dental College (LM&DC), Lahore, Pakistan Author
  • Fatima Maheen Lahore Medical & Dental College (LM&DC), Lahore, Pakistan Author
  • Nimra Niaz Lahore Medical & Dental College (LM&DC), Lahore, Pakistan Author
  • Rabia Arooj Center For Applied Molecular Biology (CAMB), University of the Punjab, Lahore, Pakistan Author
  • Mahwish Bibi Center For Applied Molecular Biology (CAMB), University of the Punjab, Lahore, Pakistan Author

DOI:

https://doi.org/10.69750/dmls.01.04.031

Keywords:

Hypertension ,Myocardial infarction, neural networks, predictive analytics, cardiovascular disease, risk assessment, AUC-ROC, Hyperlipidemia.

Abstract

Background: The ability to diagnose myocardial infarction at a relatively early stage is considered to be highly important with the aim of increasing patient survival rate, especially in conditions of increased risk. The existing risk assessment models are somewhat misleading in terms of predictive validity.

Objective: This study evaluates the ability of the various machine learning models in the prediction of MI with especial emphasis on the neural networks’ performance as well as the comparison with the other traditional and other types of sophisticated models.

Methods: A cross-sectional study was conducted to collect the data from Electronic Health Records (EHRs) of the high-risk patients. The machine learning algorithms chosen were logistic regression, random forest, gradient boosting machines, and neural networks. The outcomes were measured in terms of accuracy, sensitivity, specificity and Area under the curve of the receiver operating characteristic (AUC-ROC).

Results: Thus, as it can be seen, the neural networks proved to be the most effective as they have the highest accuracy (91.3%) and AUC-ROC of (0.95). These models have shown better predictive accuracy compared with other techniques and most of the other forms of the machine learning models.

Conclusion: Neural networks improve the early identification of MI in high-risk groups adding potential betterment in clinical prognosis. These new models are still not implemented in everyday clinical practice, and their integration could revolutionise patient management, providing earlier and better-targeted treatments.

 

Downloads

Download data is not yet available.

References

Patel SJ, Yousuf S, Padala JV, Reddy S, Saraf P, Nooh A, et al. Advancements in artificial intelligence for precision diagnosis and treatment of myocardial infarction: a comprehensive review of clinical trials and randomized controlled trials. Cureus. 2024;16(5).

Boeddinghaus J, Nestelberger T, Koechlin L, Wussler D, Lopez-Ayala P, Walter JE, et al. Early diagnosis of myocardial infarction with point-of-care high-sensitivity cardiac troponin I. J Am Coll Cardiol. 2020;75(10):1111–24.

Almansouri NE, Awe M, Rajavelu S, Jahnavi K, Shastry R, Hasan A, et al. Early diagnosis of cardiovascular diseases in the era of artificial intelligence: an in-depth review. Cureus. 2024;16(3).

Wang J, Tan GJ, Han LN, Bai YY, He M, Liu HB. Novel biomarkers for cardiovascular risk prediction. J Geriatr Cardiol. 2017;14(2):135.

Yeh RW, Sidney S, Chandra M, Sorel M, Selby JV, Go AS. Population trends in the incidence and outcomes of acute myocardial infarction. N Engl J Med. 2010;362(23):2155–65.

Wang XY, Zhang F, Zhang C, Zheng LR, Yang J. The biomarkers for acute myocardial infarction and heart failure. Biomed Res Int. 2020;2020.

Olawade DB, Aderinto N, Olatunji G, Kokori E, David-Olawade AC, Hadi M. Advancements and applications of artificial intelligence in cardiology: current trends and future prospects. J Med Surg Public Health. 2024:100109.

Roman M. Are neural networks the ultimate risk prediction models in patients at high risk of acute myocardial infarction? Eur J Prev Cardiol. 2020;27(19):2045–6.

Petit C, Bezemer R, Atallah L. A review of recent advances in data analytics for post-operative patient deterioration detection. J Clin Monit Comput. 2018;32:391–402.

Vogel B, Claessen BE, Arnold SV, Chan D, Cohen DJ, Giannitsis E, et al. ST-segment elevation myocardial infarction. Nat Rev Dis Primers. 2019;5(1):39.

Reddy K, Khaliq A, Henning RJ. Recent advances in the diagnosis and treatment of acute myocardial infarction. World J Cardiol. 2015;7(5):243.

Tanveer M, Qadeer T, Ali SY, Bhatti AA, Khalid R, Suleman M, et al. Physio-anatomical complications in short and long surgical procedures with general anesthesia: a comparative cross-sectional study. Dev Med Life Sci. 2024;1(2):20–7.

Puchner SB, Liu T, Mayrhofer T, Truong QA, Lee H, Fleg JL, et al. High-risk plaque detected on coronary CT angiography predicts acute coronary syndromes independent of significant stenosis: results from the ROMICAT-II trial. J Am Coll Cardiol. 2014;64(7):684–92.

Fronczek J, Polok K, Devereaux P, Górka J, Archbold R, Biccard B, et al. External validation of the revised cardiac risk index and NSQIP MICA calculator in noncardiac vascular surgery. Br J Anaesth. 2019;123(4):421–9.

Yu Z, Gong H, Gao Y, Li L, Xue F, Zeng Y, et al. Integrated photothermal‐pyroelectric biosensor for rapid and point-of-care diagnosis of acute myocardial infarction. Small. 2022;18(30):2202564.

Huang JB, Chen YS, Ji HY, Xie WM, Jiang J, Ran LS, et al. Neutrophil-to-HDL ratio has superior prognostic value in elderly patients with acute myocardial infarction. Lipids Health Dis. 2020;19:1–12.

Camaj A, Fuster V, Giustino G, Bienstock SW, Sternheim D, Mehran R, et al. Left ventricular thrombus following acute myocardial infarction: JACC state-of-the-art review. J Am Coll Cardiol. 2022;79(10):1010–22.

Ahmed Z. Practicing precision medicine with integrative clinical and multi-omics data analysis. Hum Genomics. 2020;14(1):35.

Stengaard C, Sørensen JT, Ladefoged SA, Lassen JF, Rasmussen MB, Pedersen CK, et al. Optimizing prehospital triage for suspected acute myocardial infarction using hs-cTnT and copeptin. Biomarkers. 2017;22(3–4):351–60.

Katus H, Ziegler A, Ekinci O, Giannitsis E, Stough WG, Achenbach S, et al. Early diagnosis of acute coronary syndrome. Eur Heart J. 2017;38(41):3049–55.

Kim ES, Sun JK, Park N, Kubzansky LD, Peterson C. Purpose in life and reduced risk of myocardial infarction in older adults. J Behav Med. 2013;36:124–33.

Jaltotage B, Sukudom S, Ihdayhid AR, Dwivedi G. Enhancing risk stratification on coronary CT angiography: the role of artificial intelligence. Clin Ther. 2023.

Giordano C, Brennan M, Mohamed B, Rashidi P, Modave F, Tighe P. Accessing artificial intelligence for clinical decision-making. Front Digit Health. 2021;3:645232.

Huang Y, Cheung CY, Li D, Tham YC, Sheng B, Cheng CY, et al. AI-integrated ocular imaging for predicting cardiovascular disease. Eye. 2024;38(3):464–72.

Mahmarian JJ, Dakik HA, Filipchuk NG, Shaw LJ, Iskander SS, Ruddy TD, et al. Intensive medical therapy vs revascularization for suppression of ischemia in survivors of MI. J Am Coll Cardiol. 2006;48(12):2458–67.

Downloads

Crossmark - Check for Updates PlumX Metrics

Published

30-06-2024

How to Cite

Tariq, F. ., Tariq, R. ., Saif, S.- e-Z. ., Saqib, R. ., Saleem, A. ., Maheen , F. ., Niaz, N. ., Arooj, R. ., & Bibi, M. . (2024). Advancements in Predictive Analytics for Early Detection of Myocardial Infarction in High-Risk Populations: Early Detection of Myocardial Infarction Using Predictive Analytics. DEVELOPMENTAL MEDICO-LIFE-SCIENCES, 1(4), 3-7. https://doi.org/10.69750/dmls.01.04.031

Share