Analysis of Patients Receiving Treatment for Inflammatory Breast Disease at Surgery Department of Tertiary Care Units
Treating Inflammatory Breast Disease in Tertiary Surgery Units
DOI:
https://doi.org/10.69750/dmls.01.01.012Keywords:
Breast abscesses, lactating women, inflammation, antibiotics, Ischemia, skin excoriation, wound sepsisAbstract
Abstract:
Background: In the Surgery Department of Tertiary Care Units, an analysis of patients receiving treatment for inflammatory breast disease presents a critical assessment of disease patterns and therapeutic outcomes. This evaluation is pivotal in understanding the prevalence and efficacy of treatment modalities in addressing complex breast conditions within specialized care settings.
Aims and Objectives: To assess the effectiveness of the care given to mastitis and breast abscess patients admitted to the surgical department of the Sir Gangaram Ram Hospital Lahore.
Study Design: Prospective Analytical Cross-sectional Study.
Place & duration of study: Current study was conducted in surgical department of the Sir Gangaram Ram Hospital Lahore from March 2023 to December 2023.
Methodology: The patients those visited and admitted with a diagnosis of breast abscess were included regardless of age, size of the abscess and co-morbidities. The patient was informed of the available treatment options, and their priority was taken into account for the chosen course of action. Total 100 female patients were divided in two different groups. In group-A 60 patients were operated with local anesthesia and their abscess size was larger than 2.5 cm in diameter. While in group-B, 40 patients were conservatively managed and either ultrasound guided aspiration or no intervention is used. Either the size of the abscess was less than 2.5 centimeters in these patients, or there were signs of inflammation without any fluctuation. Whereas in case of conservative treatment hot fomentation and antibiotics were recommended, some patients who received surgery or minimally invasive treatment also received prescriptions for antibiotics. The antibiotics used were a combination of a beta-lactamase inhibitor, clavulanic acid, and a broad spectrum penicillin, namely amoxicillin, which could be used as an adjuvant or sole therapy. If there was no need for surgery to treat the abscess, the treatment was considered successful. Bio- statistical program (SPSS) version 2022 were used for the raw data description.
Results: Total 100 female patients were considered and their aged from 20-40 years, lactating women were 42 while 58 women non-lactating. Group A consisted of 48 surgical patients who underwent incision and drainage, while Group B consisted of 52 patients who were treated conservatively. Ischemia, skin excoriation, wound sepsis, and postoperative septicemia were among the complications that were encountered during the postoperative period. Breast deformity, sinus formation, non-healing or closure, and organized abscess were diagnosed during the follow-up. There was no any mortality.
Conclusion: Surgical drainage is the only option for treating breast abscesses, both large and small, as it significantly reduces morbidity.
Downloads
References
Enkobahry A, Sime T, Kene K, Mateos T, Dilnesa S, Zawdie B. Blood biomarkers as potential malnutrition screening alternatives among adult patients with cancer on treatment in oncology unit of jimma tertiary hospital: A cross-sectional analysis. BMC nutrition. 2023;9(1):38.
Taylor GB, Paviour SD, Musaad S, Jones WO, Holland DJ. A clinicopathological review of 34 cases of inflammatory breast disease showing an association between corynebacteria infection and granulomatous mastitis. Pathology. 2003;35(2):109-19.
Jafar D, Pesnani F, Arif S, Nasir A. Self-esteem of patients receiving chemotherapy treatment in a tertiary care Hospital Karachi, Pakistan. Pakistan Journal of Medicine and Dentistry. 2020;9(3):60-4.
Ladha K, Melo MFV, McLean DJ, Wanderer JP, Grabitz SD, Kurth T, et al. Intraoperative protective mechanical ventilation and risk of postoperative respiratory complications: hospital based registry study. Bmj. 2015;351.
Chatterjee S, Chattopadhyay A, Todi SK. Outcomes of severe sepsis among adults in a tertiary care hospital in Kolkata–a preliminary study. J Anest & Inten Care Med. 2018;6(2):555684.
Lal S, Khan E, Malik MA. Practical challenges of managing COVID-19 positive patients in the adult intensive care unit of a tertiary care teaching hospital of Ireland. Anaesthesia, Pain & Intensive Care. 2020;24(3):263-71.
Partridge J, Harari D, Martin F, Peacock J, Bell R, Mohammed A, et al. Randomized clinical trial of comprehensive geriatric assessment and optimization in vascular surgery. Journal of British Surgery. 2017;104(6):679-87.
Motsisim S, Ballot DE. A review of necrotising enterocolitis in very low birth weight babies in a tertiary hospital in Johannesburg. African Journal of Paediatric Surgery. 2023;20(1):59-66.
Garassino MC, Whisenant JG, Huang L-C, Trama A, Torri V, Agustoni F, et al. COVID-19 in patients with thoracic malignancies (TERAVOLT): first results of an international, registry-based, cohort study. The Lancet Oncology. 2020;21(7):914-22.
Hamieh NM, Akel R, Anouti B, Traboulsi C, Makki I, Hamieh L, et al. Cancer-related pain: prevalence, severity and management in a tertiary care center in the Middle East. Asian Pacific Journal of Cancer Prevention: APJCP. 2018;19(3):769.
McGillicuddy E, Schuster K, Barre K, Suarez L, Hall M, Kaml G, et al. Non-operative management of acute cholecystitis in the elderly. Journal of British Surgery. 2012;99(9):1254-61.
Mei AHY, Jin WLC, Hwang MKY, Meng YC, Seng LC, Yaw WH. Value of the Palliative Performance Scale in the prognostication of advanced cancer patients in a tertiary care setting. Journal of Palliative Medicine. 2013;16(8):887-93.
Low JA, Berman AW, Steinberg SM, Danforth DN, Lippman ME, Swain SM. Long-term follow-up for locally advanced and inflammatory breast cancer patients treated with multimodality therapy. Journal of clinical oncology. 2004;22(20):4067-74.
Matthews LR, Ahmed Y, Wilson KL, Griggs DD, Danner OK. Worsening severity of vitamin D deficiency is associated with increased length of stay, surgical intensive care unit cost, and mortality rate in surgical intensive care unit patients. The American journal of surgery. 2012;204(1):37-43.
Lim B, Woodward WA, Wang X, Reuben JM, Ueno NT. Inflammatory breast cancer biology: the tumour microenvironment is key. Nature Reviews Cancer. 2018;18(8):485-99.
Chaparro M, Verreth A, Lobaton T, Gravito-Soares E, Julsgaard M, Savarino E, et al. Long-term safety ofin uteroexposure to anti-TNFα drugs for the treatment of inflammatory bowel disease: Results from the multicenter European TEDDY study. Official journal of the American College of Gastroenterology| ACG. 2018;113(3):396-403.
Wolfrum A, Kümmel S, Theuerkauf I, Pelz E, Reinisch M. Granulomatous mastitis: a therapeutic and diagnostic challenge. Breast care. 2018;13(6):413-8.
He Y, Wong YWY, Ngeow AJH, Sim EY, Cherng BPZ, Arunachalam S, et al. Preparation and consideration for establishment of an isolation maternity unit in a tertiary hospital during COVID-19 pandemic. BMC Pregnancy and Childbirth. 2022;22(1):317.
Senkus E, Kyriakides S, Ohno S, Penault-Llorca F, Poortmans P, Rutgers E, et al. Primary breast cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Annals of oncology. 2015;26:v8-v30.
Kepkey BB. Barriers to and facilitators of adherence to intravenous chemotherapy among breast cancer patients at a tertiary hospital in the Western Cape: Stellenbosch: Stellenbosch University; 2022.
Moletta L, Pierobon ES, Capovilla G, Costantini M, Salvador R, Merigliano S, et al. International guidelines and recommendations for surgery during Covid-19 pandemic: a systematic review. International Journal of Surgery. 2020;79:1808.
PlumX Metrics
Published
Issue
Section
License
Copyright (c) 2024 DEVELOPMENTAL MEDICO-LIFE-SCIENCES
This work is licensed under a Creative Commons Attribution 4.0 International License.
The Author(s) 2024. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/public domain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
