Prevalence and Risk Factors of Chronic Otitis Media Among Pediatric Patients Attending Tertiary Care Hospitals: A Cross-Sectional Study
Epidemiology and Determinants in a Pediatric Population
DOI:
https://doi.org/10.69750/dmls.03.02.0190Keywords:
Chronic Otitis Media, Pediatrics, Risk Factors, Prevalence, Hearing Loss, Upper Respiratory Tract InfectionsAbstract
Background: Chronic otitis media (COM) is an inflammatory disease of the middle ear that is persistent and a major cause of preventable hearing loss in children, especially in countries with low and middle incomes. Its great prevalence is strictly connected with socioeconomic, environmental, and nutritional factors.
Objective: To identify the prevalence and risk factors that are linked with chronic otitis media in pediatric patients in a tertiary care hospital.
Methods: This cross-sectional study was conducted at General Hospital, Lahore, Pakistan, between June 2022 and March 2025. A total of 150 children aged 1 to 15 years were recruited using a consecutive sampling technique. The diagnosis of COM was established based on clinical findings, including perforation of the tympanic membrane and/or otorrhea persisting for more than 12 weeks. Data on demographic characteristics, socioeconomic status, environmental exposures, nutritional status, breastfeeding history, and recurrent upper respiratory tract infections were collected. Statistical analysis was performed using SPSS version 26. The chi-square test and multivariate logistic regression were applied, and a p-value of ≤ 0.05 was considered statistically significant.
Results: The incidence of COM was 29.3%. There were significant correlations with low socioeconomic status (p = 0.002), frequent infection of the upper respiratory tract (p < 0.001), indoor smoke exposure (p = 0.003), malnutrition (p = 0.001), and absence of exclusive breastfeeding (p = 0.015). Recurrent infections (AOR = 3.4), malnutrition (AOR = 2.9), and exposure to indoor smoke (AOR = 2.6) were found to be independent predictors using multivariate analysis.
Conclusion: Chronic otitis media is quite common in children, and it is closely linked to the modifiable risk factors, which creates the necessity of preventive strategies and early intervention.
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Tesfa T, Mitiku H, Sisay M, et al. Bacterial otitis media in sub-Saharan Africa: a systematic review and meta-analysis. BMC Infect Dis. 2020;20(1):225. doi:10.1186/s12879-020-4950-y
Khan J, Paul S, Chowdhury CS, Mostafa MG. Bacteriology of chronic suppurative otitis media at a tertiary care hospital, Mymensingh. Mymensingh Med J. 2020;29:545-552.
Alam M, Beig S, Sultan A, Chandra K. Bacteriological and antibiotic sensitivity profile of cholesteatomatous otitis media in pediatric and adult population: prevailing scenario in Northern India. Indian J Otolaryngol Head Neck Surg. 2020;74 Suppl 1. doi:10.1007/S12070-020-01956-0
Sandhu D, Gupta V, Chhina D, Munjal M. Clinical characterisation and microbiological profile of otological infections. IP Int J Med Microbiol Trop Dis. 2020;6:96-102. doi:10.18231/J.IJMMTD.2020.021
Sah BP, Chettri ST, Bhattarai NR, et al. Microbiological profile and their antibiotic sensitivity pattern in patients of chronic suppurative otitis media at the Eastern Tertiary Care Center of Nepal. IP J Otorhinolaryngol Allied Sci. 2020. doi:10.18231/J.IJOAS.2020.019
Maharjan M, Phuyal S, Shrestha M, Bajracharya R. Chronic otitis media and subsequent hearing loss in children from the Himalayan region residing in Buddhist monastic schools of Nepal. J Otol. 2020;15:144-148. doi:10.1016/j.joto.2020.09.001
Enoksson F, Ruiz Rodriguez A, Peno C, et al. Niche- and gender-dependent immune reactions in relation to the microbiota profile in pediatric patients with otitis media with effusion. Infect Immun. 2020;88:e00147-20. doi:10.1128/IAI.00147-20
Khatun MR, Alam KMF, Naznin M, Salam MA. Microbiology of chronic suppurative otitis media: an update from a tertiary care hospital in Bangladesh. Pak J Med Sci. 2021;37(3):821-826. doi:10.12669/pjms.37.3.3942
Shwetha DC, Ravi GC, Venkatesha D, Megha S, Greeshma PG. Microbiological profile of chronic suppurative otitis media and their antibiogram in a rural tertiary care hospital. Int J Curr Microbiol Appl Sci. 2021;10(8):448-455. doi:10.20546/IJCMAS.2021.1008.055
Gupta S, Kumbhat P. Microbiology of chronic otitis media and shifting trends of its antibiotic susceptibility: a prospective observational study in a tertiary care institute of western Rajasthan. Indian J Otolaryngol Head Neck Surg. 2021. doi:10.1007/S12070-021-02531-X
Alam M, Sultan A, Chandra K. Microbiological assessment of chronic otitis media: aerobic culture isolates and their antimicrobial susceptibility patterns. Indian J Otolaryngol Head Neck Surg. 2021. doi:10.1007/S12070-021-02496-X
Agha ZHM, Al-Delaimi MS. Prevalence of common bacterial etiology and antimicrobial susceptibility pattern in patients with otitis media in Duhok Province, Iraq. Zanco J Pure Appl Microbiol. 2021;33(4):11-25.
Hidayat R. Pathophysiological to clinical aspects of chronic suppurative otitis media (CSOM): narrative literature review. Arch Med Case Rep. 2022;3(2):246-255.
Bhatia R, Chauhan A, Kaur K, Rana M, Pradhan P, Singh M. Prevalence of ear infections in children (0 to 15 years) of India: a systematic review and meta-analysis. Int Arch Public Health Community Med. 2022;6:080. doi:10.23937/2643-4512/1710080
Riaz N, Ajmal M, Khan MS. Frequency of otitis media with effusion among children aged 1-5 years presenting to the immunization center of tertiary care hospitals, Rawalpindi. World J Otorhinolaryngol Head Neck Surg. 2022;8:315-320. doi:10.1016/j.wjorl.2021.03.002
Restuti RD, Tamin S, Nugroho DA, Hutauruk SM, Mansyur M. Factors affecting the occurrence of otitis media with effusion in preschool and elementary school children: a comparative cross-sectional study. BMJ Open. 2022;12:e065291. doi:10.1136/bmjopen-2022-065291
Jamal A, Alsabea A, Tarakmeh M. Effect of ear infections on hearing ability: a narrative review on the complications of otitis media. Cureus. 2022;14:e27400. doi:10.7759/cureus.27400
Ahmed I, Lakhiar AA, Yousuf S, Kumar A, Ashraf MA, Chaudhry AR. Risk factors of acute otitis media in early age: a meta-analysis. Pak J Med Health Sci. 2022;16:1212. doi:10.53350/pjmhs221631212
Raza MS, Sangi R, Hanif S, Haque T, Jamro S, Memon MH. Prevalence of acute otitis media in febrile children at a tertiary care hospital. Pak J Med Health Sci. 2022;16:214. doi:10.53350/pjmhs22164214
Khairkar M, Deshmukh P, Maity H, et al. Chronic suppurative otitis media: a comprehensive review of epidemiology, pathogenesis, microbiology, and complications. Cureus. 2023;15(8):e43729. doi:10.7759/cureus.43729
Taoussi AA, Malloum MSM, Ali YA. Prevalence and clinico-bacteriological aspects of chronic suppurative otitis media at the Renaissance University Hospital in N’Djamena, Chad. Egypt J Otolaryngol. 2023;39(1):72. doi:10.1186/s43163-023-00437-9
Jin Y, Yang X, Sun H, et al. Global, regional, and national burdens of otitis media from 1990 to 2019: a population-based study. Ear Hear. 2024;45:658-665. doi:10.1097/AUD.0000000000001453
Puricelli MD. Comprehensive management of chronic ear disease: consecutive patient analysis at a tertiary children’s hospital. Int J Pediatr Otorhinolaryngol. 2024;186:112118. doi:10.1016/j.ijporl.2024.112118
Guteta ET, Abdi FA, Feyisa SG, et al. Bacterial etiologies, antimicrobial susceptibility profiles and associated factors among patients with otitis media referred to Nekemte Public Health Research and Referral Laboratory Center, Western Ethiopia: a cross-sectional study. BMC Microbiol. 2025;25:6. doi:10.1186/s12866-024-03664-z
Onifade A, Wa Katolo H, Mookerjee S, Bhutta MF. Epidemiology of chronic suppurative otitis media: systematic review to estimate global prevalence. J Epidemiol Glob Health. 2025;15(1):55. doi:10.1007/s44197-025-00396-9
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